Panters jagged antihero was made our12/19/2023 ![]() *These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products. View information about Jagged 2 on įor research use only. Skeletrophin binds the intracellular regions of Jagged-2, but not those of Delta-1,3,4, or Jagged-1.ġ. Notch1/Jagged-2 signaling system plays an important role for male germ cells to differentiate. There is growing evidence that signals transmitted through different Notch ligands can differentially affect the target cells. They regulate cell fate decision for various cell development, including myogenesis, neurogenesis, and lymphocyte development. The Notch receptors and their ligands are highly conserved signaling molecules throughout development. After a single transmembrane domain (TM) is a short in PubMedĪ single pass transmembrane protein consisting of a large extracellular N-terminal which includes the DSL domain, followed by a tandem array of EGF-like repeats (ELRs) and cysteine-rich domain (CRD). (PubMed link indicates BioLegend citation) Green Laser (532 nm)/Yellow-Green Laser (561 nm) It is recommended that the reagent be titrated for optimal performance for each application. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10 6 cells in 100 µl volume. Do not freeze.Įach lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The antibody solution should be stored undiluted between 2☌ and 8☌, and protected from prolonged exposure to light. The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. ![]()
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